Anal Cancer

HIV-associated anal cancer

HIV-associated anal carcinoma, a non-AIDS-defining cancer, is a human papillomavirus-associated malignancy with a spectrum of preinvasive changes. The standardized incidence ratio for anal cancer in patients with HIV/AIDS is 20-50. Algorithms for anal cancer screening include anal cytology followed by high-resolution anoscopy for those with abnormal findings. Outpatient topical treatments for a...

Incidence of Anal Cancer

human papillomavirus (hpv) is the most prevalent sexually transmitted infection. It is more common than herpes and chlamydia and it has been estimated that more than 75% of sexually active adolescents and adults between the ages of 15 and 49 will acquire at least one type of hpv infection. The infection is practically guaranteed in people with more than five sex partners in their lifetime. More...

Human papillomaviruses and anal cancer.

Photodynamic therapy for anal cancer.

Invasive anal cancers are generally successfully treated by combined chemotherapy with radiation therapy (XRT). For those patients who locally fail this intervention many are salvaged by surgery which generally results in permanent colostomy. We examined the treatment and outcome of Photofrin based photodynamic therapy (PDT) in a cohort of patients with anal cancer who failed locally despite ch...

Changing nature of anal cancer.

Anal cancer is rare, accounting for about 2% of all anorectal cancers or 300 cases a year in Britain.' Epidemiological studies from the United States have highlighted the striking association of syphilis and anal warts with anal cancer in unmarried men.23 Gonorrhoea, syphilis, and anal warts are more common in homosexual than heterosexual men,4 and carcinoma in situ may develop in the anal wart...